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1.
J Biomed Opt ; 28(12): 125001, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38074214

RESUMO

Significance: The database for multipulse retinal damage thresholds for the laser safety standard (IEC 60825-1:2014) is confined, especially for elongated irradiation profiles. To ensure eye safety, retinal damage thresholds (ED50 values) need to be determined. Aim: This study aims to examine nanosecond multipulse scenarios. Approach: To determine ED50 values in ex vivo measurements, an optical laser setup is presented. Porcine explant tissue is irradiated with rectangular top-hat profiles. Thermal simulations are carried out on a validated computer model and retinal injury thresholds are obtained. Results: The measurements resulted in ED50 values from 8.46 to 42.72 µJ with a slope from 1.15 to 1.4. A thermal damage in the measurements can be excluded due to the level value in combination with a different type of declining behavior for increasing pulses compared to the simulations. A dependence with increasing elongation or area of the retinal image emerges in the simulations but could not be confirmed in the measurements due to the influencing factors (biological variability, focusing, and measuring procedure). Conclusions: Using slit apertures for beam shaping, variable rectangular spot geometries are realized without changing elements in the setup. For further evaluation of the behavior of elongated irradiation profiles, additional measurements to improve the measurement accuracy are necessary.


Assuntos
Doenças Retinianas , Suínos , Animais , Doenças Retinianas/diagnóstico por imagem , Lasers , Simulação por Computador , Retina/diagnóstico por imagem
2.
J Biophotonics ; 14(2): e202000339, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-33188576

RESUMO

Lasers with wavelengths in the visible and near infrared region, pose a potential hazard to vision as the radiation can be focused on the retina. The laser safety standard IEC 60825-1:2014 provides limits and evaluation methods to perform a classification for such systems. An important parameter is the retinal spot size which is described by the angular subtense of the apparent source. In laser safety evaluations, the radiation is often described as a Gaussian beam and the image on the retina is calculated using the wave optical propagation through a thin lens. For coherent radiation, this method can be insufficient as the diffraction effects of the pupil aperture influence the retinal image. In this publication, we analyze these effects and propose a general analytical calculation method for the angular subtense. The proposed formula is validated for collimated and divergent Gaussian beams.


Assuntos
Lasers , Luz , Simulação por Computador , Distribuição Normal , Retina/diagnóstico por imagem
3.
Biomed Tech (Berl) ; 57(3): 175-84, 2012 May 31.
Artigo em Inglês | MEDLINE | ID: mdl-22691425

RESUMO

In the growing field of pico-projectors, laser-based scanning systems may be advantageous over DLP- or LCoS-based imagers due to their potential for miniaturization, enhanced optical efficiency and cost reduction. The high energy density of a combined laser beam can, however, be hazardous to the human eye. Laser projection systems must therefore be identified with the laser class, depending on their maximum optical output power. This power limits the brightness of the displayed image, which is of particular interest for mobile applications. Various approaches to classifying laser devices by their wavelength and output power are described within the standards for laser safety. It is found that actual safety regulations cannot be directly applied to scanning systems. A detailed analysis of the optical conditions in terms of a two-dimensional extended light source is appropriate for the consideration of laser scanner devices. In this article, alternative ways of applying laser standards for scanning systems are discussed. The dependencies of maximum luminous flux from scanning system parameters are reviewed. It is shown that the evaluation of retinal light exposure in terms of existing laser regulations leads to an overestimation of the hazardous potential. Advanced investigations are proposed to support the definition of suitable criteria for the classification of laser scanning projectors.


Assuntos
Traumatismos Oculares/etiologia , Traumatismos Oculares/fisiopatologia , Lasers/efeitos adversos , Lasers/normas , Lesões por Radiação/etiologia , Lesões por Radiação/fisiopatologia , Proteção Radiológica/normas , Traumatismos Oculares/prevenção & controle , Alemanha , Guias como Assunto , Modelos Biológicos , Lesões por Radiação/prevenção & controle
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